Benford Mafuvadze Selected Research

Ro 48-8071

1/2016	Cholesterol biosynthesis inhibitor RO 48-8071 suppresses growth of hormone-dependent and castration-resistant prostate cancer cells.
7/2014	Cholesterol biosynthesis inhibitors as potent novel anti-cancer agents: suppression of hormone-dependent breast cancer by the oxidosqualene cyclase inhibitor RO 48-8071.

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Benford Mafuvadze Research Topics

Disease

12	Neoplasms (Cancer) 01/2018 - 08/2011
11	Breast Neoplasms (Breast Cancer) 01/2018 - 09/2010
2	Neoplasm Metastasis (Metastasis) 01/2018 - 01/2017
2	Carcinogenesis 02/2016 - 08/2011
1	Prostatic Neoplasms (Prostate Cancer) 01/2016
1	Carcinoma (Carcinomatosis) 01/2015
1	Breast Diseases (Breast Disease) 08/2012
1	Hyperplasia 08/2011

Drug/Important Bio-Agent (IBA)

8	Progestins (Progestagens)IBA 01/2017 - 09/2010
7	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2018 - 09/2010
7	Hormones (Hormone)IBA 01/2018 - 09/2010
7	Medroxyprogesterone Acetate (Depo-Provera)FDA LinkGeneric 01/2017 - 09/2010
7	Estrogens (Estrogen)FDA Link 01/2017 - 09/2010
5	Proteins (Proteins, Gene)FDA Link 01/2018 - 09/2010
5	Progesterone CongenersIBA 01/2017 - 09/2010
4	EnzymesIBA 01/2016 - 07/2014
4	FlavonoidsIBA 01/2015 - 08/2011
4	ApigeninIBA 01/2013 - 09/2010
3	Estrogen ReceptorsIBA 01/2016 - 07/2014
3	CholesterolIBA 01/2016 - 07/2014
3	Angiogenesis Inducing Agents (Angiogenesis Factor)IBA 01/2015 - 08/2011
2	Pharmaceutical PreparationsIBA 01/2018 - 01/2016
2	LuteolinIBA 02/2016 - 01/2015
2	SteroidsIBA 01/2016 - 10/2014
2	Ro 48-8071IBA 01/2016 - 07/2014
2	LigandsIBA 01/2016 - 10/2014
2	FumaratesIBA 01/2016 - 07/2014
2	Messenger RNA (mRNA)IBA 10/2014 - 09/2010
2	lanosterol synthaseIBA 10/2014 - 07/2014
2	9,10-Dimethyl-1,2-benzanthraceneIBA 01/2013 - 08/2011
1	eprenetapoptIBA 01/2018
1	PhosphatidylserinesIBA 01/2018
1	Tumor Suppressor Protein p53IBA 01/2018
1	Norethindrone (Norethisterone)FDA LinkGeneric 01/2017
1	Androgen Receptors (Androgen Receptor)IBA 01/2016
1	Aldehyde DehydrogenaseIBA 01/2015
1	ImmunosorbentsIBA 01/2015
1	Chemokine CXCL1IBA 01/2015
1	CytokinesIBA 01/2015
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2015
1	AndrogensIBA 10/2014
1	Biological ProductsIBA 10/2014
1	lissamine rhodamine B (sulforhodamine B)IBA 07/2014
1	Fluvastatin FDA Link 07/2014
1	Simvastatin (Zocor)FDA LinkGeneric 07/2014
1	Phytoestrogens (Phytoestrogen)IBA 01/2013
1	RANK LigandIBA 08/2012
1	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 01/2012
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 01/2012
1	Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA 08/2011
1	flavoneIBA 09/2010
1	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 09/2010
1	Mifepristone (RU 486)FDA Link 09/2010
1	Progesterone Receptors (Progesterone Receptor)IBA 09/2010

Therapy/Procedure

6	Therapeutics 01/2018 - 09/2010
6	Hormone Replacement Therapy (Therapy, Hormone Replacement) 01/2017 - 08/2011
1	Aftercare (After-Treatment) 02/2016
1	Castration 01/2016
1	Drug Therapy (Chemotherapy) 01/2016